Unlocking Transcription Factors to Address Unmet Medical Need

Unlocking theTherapeutic Power of Transcription Factors

Transcription factors regulate the expression of hundreds of genes and play central roles in development, immunity and disease. Yet they've long been considered 'undruggable' due to their lack of defined binding pockets and complex structural dynamics.

At Altay, we've developed a therapeutic area-agnostic drug discovery platform that challenges this notion. By identifying novel allosteric sites - emerging only through dynamic structural changes in transcription factors - we design highly-selective small molecule inhibitors with the potential to be first- or best-in-class.